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After adjusting for education,the relative risk for AD in ERT users as compared with nonusers was 0.46(95%CI,0.209-0.997),indicating a reduced risk of AD for woman who had reported the use of estrogen.Our data did not show an effect for duration of ERT usage.Our finding offers additional support for a protective influence of estrogen in AD.Randomized clinical trials are necessary to confirm this association,which could have a significant public health impact. |
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